The Anticonvulsant Lamotrigine Reduces Bout-Like Alcohol Drinking in Rats-Reference-Cited by-同舟云学术

The Anticonvulsant Lamotrigine Reduces Bout-Like Alcohol Drinking in Rats

Published:2021-10-28 Issue: Volume: Page:
ISSN:0735-0414
Container-title:Alcohol and Alcoholism
language:en
Short-container-title:

Author:

Poceviciute Ieva¹,Buisas Rokas¹,Danelius Tadas²,Dulinskas Redas¹,Ruksenas Osvaldas¹,Vengeliene Valentina¹^ORCID

Affiliation:

1. Department of Neurobiology and Biophysics, Institute of Biosciences, Life Sciences Center, Vilnius University, Sauletekio ave. 7, LT-10257 Vilnius, Lithuania

2. Institute of Applied Mathematics, Faculty of Mathematics and Informatics, Vilnius University, Naugarduko g. 24, LT-03225 Vilnius, Lithuania

Abstract

Abstract We used an optical lickometer system to study drinking microstructure and effect of lamotrigine in voluntary alcohol-drinking rats. We showed that, similar to humans, animals differ by their drinking microstructure where some consume alcohol exclusively in a bout-like patterns. The study suggests that anticonvulsants, such as lamotrigine, may be one treatment strategy specifically affecting this type of drinking.

Funder

Research Council of Lithuania

Lithuanian Business Support Agency

Publisher

Oxford University Press (OUP)

Subject

General Medicine

Link

http://academic.oup.com/alcalc/advance-article-pdf/doi/10.1093/alcalc/agab073/41010169/agab073.pdf

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