Evaluating Craving in Alcohol Use Disorder: Psychometric Characteristics of the Craving Typology Questionnaire-15 (CTQ-15)

Author:

Martinotti Giovanni12,Festa Giuseppe Manuel34,Ceci Franca1,Di Muzio Ilenia1,Callea Antonino5,Capparelli Ada5,Bonifaci Ludovica5,Chillemi Eleonora6,Pepe Maria7,Pettorruso Mauro1,Chiappini Stefania12,Di Nicola Marco78,Janiri Luigi5

Affiliation:

1. Department of Neurosciences, Imaging and Clinical Sciences, University “G. D’Annunzio” of Chieti-Pescara , Via dei Vestini 31, Chieti 66100 , Italy

2. Psychopharmacology, Drug Misuse and Novel Psychoactive Substances Research Unit, School of Life and Medical Sciences, University of Hertfordshire , Hatfield AL10 9AB , UK

3. Pontifical Faculty of Educational Sciences «AUXILIUM» , Via Cremolino 141, Rome 00166 , Italy

4. Interdisciplinary Institute of Advanced Clinical Training «IACT» , Rome 00186 , Italy

5. Department of Human Science, Lumsa University , Borgo S. Angelo 13, Rome 00193 , Italy

6. Villa Maria Pia Psychiatric Hospital , Via del Forte Trionfale 36, Rome 00135 , Italy

7. Department of Neuroscience, Section of Psychiatry, Università Cattolica del Sacro Cuore , Rome, 00168 , Italy

8. Department of Psychiatry, Fondazione Policlinico Universitario Agostino Gemelli IRCCS , Rome, 00168 , Italy

Abstract

Abstract Aims The Craving Typology Questionnaire (CTQ) is a psychometric instrument used to assess alcohol craving in normal controls and subjects with alcohol use disorder (AUD). It allows a dimensional self-rating assessment of craving according to a three-pathway psychobiological model of craving distinguishing craving into a reward, relief and obsessive component. The aim of the present study is to evaluate psychometric properties of the CTQ-15, a revised version of CTQ with 15 items. Methods The CTQ-15 was firstly administered to two groups of control subjects, one (414 subjects) used for the exploratory factor analysis and the other one (415 subjects) for the confirmatory factor analysis. A three-factor model was assessed and compared to alternative models. Results The resulting structure was in line with the original scale CTQ. Obsessive craving accounted for 15.20% of the total variance, relief craving for the 13.99% and reward craving for 13.13% of the total variance. The three-factor model (M1) reached good fit indices (CFI = 0.96, TLI = 0.95, RMSEA = 0.06 and SRMR = 0.05) and was significantly better than other alternative models. Reliability showed good internal consistency for each scale, i.e. obsessive craving (α = 0.92), relief craving (α = 0.82) and reward craving (α = 0.81). Conclusions The CTQ-15 proved to be reliable and practical for identifying the three dimensions of craving in clinical practice. Craving plays a crucial role in the mechanisms of dependence and relapse; thus, characterizing the craving can be fundamental to a targeted drug therapy.

Publisher

Oxford University Press (OUP)

Subject

General Medicine

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