Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation

Author:

van der Pluijm Ingrid12,Burger Joyce23,van Heijningen Paula M2,IJpma Arne4,van Vliet Nicole2,Milanese Chiara2,Schoonderwoerd Kees3,Sluiter Willem2,Ringuette Lea-Jeanne5,Dekkers Dirk H W6,Que Ivo7,Kaijzel Erik L7,te Riet Luuk18,MacFarlane Elena G9,Das Devashish2,van der Linden Reinier10,Vermeij Marcel11,Demmers Jeroen A6,Mastroberardino Pier G2,Davis Elaine C5,Yanagisawa Hiromi12,Dietz Harry C91314,Kanaar Roland1516,Essers Jeroen11516

Affiliation:

1. Department of Vascular Surgery, Erasmus MC, Wytemaweg 80, CN Rotterdam, The Netherlands

2. Department of Molecular Genetics, Erasmus MC, Wytemaweg 80, CN Rotterdam, The Netherlands

3. Department of Clinical Genetics, Erasmus MC, Wytemaweg 80, CN Rotterdam, The Netherlands

4. Clinical Bioinformatics Unit, Department of Pathology, Erasmus MC, Wytemaweg 80, CN Rotterdam, The Netherlands

5. Department of Anatomy and Cell Biology, McGill University, Rue University, Montréal, QC H3A 0C7, Canada

6. Proteomics Center, Erasmus MC, Wytemaweg 80, CN Rotterdam, The Netherlands

7. Department of Radiology, Leiden University Medical Center, Albinusdreef 2, ZA Leiden, The Netherlands

8. Department of Pharmacology, Erasmus MC, Wytemaweg 80, CN Rotterdam, The Netherlands

9. Department of Surgery, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD, USA

10. Stem cell Institute, Erasmus MC, Wytemaweg 80, CN Rotterdam, The Netherlands

11. Department of Pathology, Erasmus MC, Wytemaweg 80, CN Rotterdam, The Netherlands

12. Life Science Center, Tsukuba Advanced Research Alliance, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan

13. Institute of Genetic Medicine, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD, USA

14. Division of Pediatric Cardiology, Department of Pediatrics, and Department of Medicine, Johns Hopkins University School of Medicine, 733 N Broadway, Baltimore, MD, USA

15. Department of Radiation Oncology, Erasmus MC, Wytemaweg 80, CN Rotterdam, The Netherlands

16. Department of Molecular Genetics, Oncode Institute, Erasmus MC, Rotterdan, The Netherlands

Funder

Lijf en Leven

DIVERS

Lijf and Leven

ZonMW

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

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