1. Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa , Pisa , Italy
2. Department of Pharmacology and Physiology, Karolinska Institutet , Stockholm , Sweden
3. Department of Perioperative Medicine and Intensive Care (PMI), Karolinska University Hospital , Stockholm , Sweden
4. Centre for Medical Sciences – CISMed, University of Trento , Trento , Italy
5. Anesthesia and Intensive Care, Santa Chiara Regional Hospital , APSS Trento , Italy