Relative contribution of morphine and morphine-6-glucuronide to the analgesic effect after morphine administration
Author:
Publisher
Elsevier BV
Subject
Anesthesiology and Pain Medicine
Link
http://academic.oup.com/bja/article-pdf/114/6/1007/704715/aev132.pdf
Reference7 articles.
1. Morphine-6-glucuronide is responsible for the analgesic effect after morphine administration: a quantitative review of morphine, morphine-6-glucuronide, and morphine-3-glucuronide;Klimas;Br J Anaesth,2014
2. Morphine metabolism, transport and brain disposition;Gregori;Metab Brain Dis,2012
3. Evidence for P-glycoprotein- modulated penetration of morphine-6-glucuronide into brain capillary endothelium;Huwyler;Br J Pharmacol,1996
4. Association of UGT2B7 and ABCB1 genotypes with morphine-induced adverse drug reactions in Japanese patients with cancer;Fujita;Cancer Chemother Pharmacol,2010
5. Cyclosporine-inhibitable blood-brain barrier drug transport influences clinical morphine pharmacodynamics;Meissner;Anesthesiology,2013
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