Effects of Mutation at Methionine-42 of Escherichia coli Dihydrofolate Reductase on Stability and Function: Implication of Hydrophobic Interactions
Author:
Publisher
Oxford University Press (OUP)
Subject
Molecular Biology,Biochemistry,General Medicine
Link
http://academic.oup.com/jb/article-pdf/137/5/643/2296707/mvi079.pdf
Reference35 articles.
1. Sawaya, M.R. and Kraut, J. (1997) Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry36, 586–603
2. Kitahara, R., Sareth, S., Yamada, H., Ohmae, E., Gekko, K., and Akasaka, K. (2000) High pressure NMR reveals active-site hinge motion of folate-bound Escherichia coli dihydrofolate reductase. Biochemistry39, 12789–12795
3. Gekko, K., Yamagami, K., Kunori, Y., Ichihara, S., Kodama, M., and Iwakura, M. (1993) Effects of point mutation in a flexible loop on the stability and enzymatic function of Escherichia coli dihydrofolate reductase. J. Biochem.113, 74–80
4. Gekko, K., Kunori, Y., Takeuchi, H., Ichihara, S., and Kodama, M. (1994) Point mutations at glycine-121 of Escherichia coli dihydrofolate reductase: important roles of a flexible loop in the stability and function. J. Biochem.116, 34–41
5. Cameron, C.E. and Benkovic, S.J. (1997) Evidence for a functional role of the dynamics of glycine-121 of Escherichia coli dihydrofolate reductase obtained from kinetic analysis of a site-directed mutant. Biochemistry36, 15792–15800
Cited by 17 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Intramolecular charge transfer and the function of vibronic excitons in photosynthetic light harvesting;Photosynthesis Research;2024-04-24
2. Effects of Distal Mutations on Ligand-Binding Affinity in E. coli Dihydrofolate Reductase;ACS Omega;2021-10-01
3. Encapsulin Nanocontainers as Versatile Scaffolds for the Development of Artificial Metabolons;ACS Synthetic Biology;2021-03-26
4. High-pressure protein crystal structure analysis of Escherichia coli dihydrofolate reductase complexed with folate and NADP+;Acta Crystallographica Section D Structural Biology;2018-09-01
5. Vacuum-Ultraviolet Circular Dichroism Spectra of Escherichia coli Dihydrofolate Reductase and Its Mutants: Contributions of Phenylalanine and Tyrosine Side Chains and Exciton Coupling of Two Tryptophan Side Chains;The Journal of Physical Chemistry B;2015-10-01
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3