Author:
Knapp Emily A,Kress Amii M,Parker Corette B,Page Grier P,McArthur Kristen,Gachigi Kennedy K,Alshawabkeh Akram N,Aschner Judy L,Bastain Theresa M,Breton Carrie V,Bendixsen Casper G,Brennan Patricia A,Bush Nicole R,Buss Claudia,Camargo, Jr. Carlos A,Catellier Diane,Cordero José F,Croen Lisa,Dabelea Dana,Deoni Sean,D’Sa Viren,Duarte Cristiane S,Dunlop Anne L,Elliott Amy J,Farzan Shohreh F,Ferrara Assiamira,Ganiban Jody M,Gern James E,Giardino Angelo P,Towe-Goodman Nissa R,Gold Diane R,Habre Rima,Hamra Ghassan B,Hartert Tina,Herbstman Julie B,Hertz-Picciotto Irva,Hipwell Alison E,Karagas Margaret R,Karr Catherine J,Keenan Kate,Kerver Jean M,Koinis-Mitchell Daphne,Lau Bryan,Lester Barry M,Leve Leslie D,Leventhal Bennett,LeWinn Kaja Z,Lewis Johnnye,Litonjua Augusto A,Lyall Kristen,Madan Juliette C,McEvoy Cindy T,McGrath Monica,Meeker John D,Miller Rachel L,Morello-Frosch Rachel,Neiderhiser Jenae M,O’Connor Thomas G,Oken Emily,O’Shea Michael,Paneth Nigel,Porucznik Christina A,Sathyanarayana Sheela,Schantz Susan L,Spindel Eliot R,Stanford Joseph B,Stroustrup Annemarie,Teitelbaum Susan L,Trasande Leonardo,Volk Heather,Wadhwa Pathik D,Weiss Scott T,Woodruff Tracey J,Wright Rosalind J,Zhao Qi,Jacobson Lisa P,Influences on Child Health Outcomes , on behalf of program collaborators for Environmental
Abstract
Abstract
The Environmental Influences on Child Health Outcomes (ECHO)-Wide Cohort Study (EWC), a collaborative research design comprising 69 cohorts in 31 consortia, was funded by the National Institutes of Health (NIH) in 2016 to improve children’s health in the United States. The EWC harmonizes extant data and collects new data using a standardized protocol, the ECHO-Wide Cohort Data Collection Protocol (EWCP). EWCP visits occur at least once per life stage, but the frequency and timing of the visits vary across cohorts. As of March 4, 2022, the EWC cohorts contributed data from 60,553 children and consented 29,622 children for new EWCP data and biospecimen collection. The median (interquartile range) age of EWCP-enrolled children was 7.5 years (3.7–11.1). Surveys, interviews, standardized examinations, laboratory analyses, and medical record abstraction are used to obtain information in 5 main outcome areas: pre-, peri-, and postnatal outcomes; neurodevelopment; obesity; airways; and positive health. Exposures include factors at the level of place (e.g., air pollution, neighborhood socioeconomic status), family (e.g., parental mental health), and individuals (e.g., diet, genomics).
Publisher
Oxford University Press (OUP)