Validation of the Liver Transplant Risk Score in Europe

Author:

Ashwat Eishan1,Kaltenmeier Christof1,Liu Hao1,Reddy Dheera1,Thompson Ann1,Dharmayan Stalin2,Ayloo Subhashini3,Nadalin Silvio4,Ciccarelli Olga5,Xu Qingyong16,Adam Rene7,Karam Vincent7,Zieniewicz Krzystof8,Mirza Darius9,Heneghan Michael10,Romagnoli Renato11ORCID,Paul Andreas12,Cherqui Daniel7,Pratschke Johann13,Boudjema Karim14ORCID,Schemmer Peter15,Rodriguez Fernando San Juan16,Lodge Peter17ORCID,de Simone Paolo18,Bachellier Phillippe19,Fronek Jiri20,Fondevila Constantino21,Molinari Michele1

Affiliation:

1. Department of Surgery, University of Pittsburgh Medical Center , Pittsburgh, Pennsylvania , USA

2. Department of Surgery, Leicester General Hospital , Leicester , UK

3. Department of Surgery, Brown University , Providence, Rhode Island , USA

4. Department of Surgery, Eberhard Karls University of Tubingen University , Tubingen , Germany

5. Department of Surgery, Cliniques Universitaires Saint Luc , Brussels , Belgium

6. Department of Pathology, University of Pittsburgh Medical Center , Pittsburgh, Pennsylvania , USA

7. Department of Surgery, Hospital Paul Brousse , Villejuif , France

8. Department of Surgery, Medical University of Warsaw , Warsaw , Poland

9. Department of Surgery, Queen Elizabeth Hospital , Birmingham , UK

10. Department of Surgery, King’s College Hospital , London , UK

11. Centro di Trapianti di Fegato, AOU Citta’ Della Salute e Della Scienza di Torino , Torino , Italy

12. Department of Surgery, CUK GHS Essen , Essen , Germany

13. Department of Surgery, Charite Campus Virchow Klinikum , Berlin , Germany

14. Department of Surgery, CHU Rennes, Hôpital de Pontchaillou , Rennes , France

15. Department of Surgery, Universitatsklinikum Heidelberg , Heidelberg , Germany

16. Department of Surgery, Hospital Universitario y Politecnico la Fe , Valencia , Spain

17. Department of Surgery, St James's University Hospital and Seacroft University Hospital , Leeds , UK

18. Department of Surgery, Ospedale Cisanello , Pisa , Italy

19. Department of Surgery, CHRU de Strasburg , Strasbourg , France

20. Transplantcenter, IKEM , Prague , Czech Republic

21. Hospital Universitario La Paz (Department of General & Digestive Surgery), Instituto de Investigación La Paz (IdiPAZ), Centro de Investigaciones Biomedicas de la Red de Enfermedades Hepaticas y Digestivas (CIBERehd) , Madrid , Spain

Abstract

The Liver Transplant Risk Score (LTRS) is a simple clinical instrument developed to predict post liver transplant outcomes based on patient characteristics measured at the time of listing. The LTRS was developed using data of adult patients transplanted in the United States. In this study, we validated the performance of the LTRS in a cohort of patients transplanted in Europe.

Publisher

Oxford University Press (OUP)

Subject

Surgery

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