Bariatric surgery volume by hospital and long-term survival: population-based NordOSCo data

Author:

Markar Sheraz R123ORCID,Santoni Giola1,Holmberg Dag1ORCID,Kauppila Joonas H14,Lagergren Jesper15ORCID

Affiliation:

1. Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital , Stockholm , Sweden

2. Department of Surgery and Cancer, Imperial College London , London , UK

3. Nuffield Department of Surgery, Oxford University , Oxford , UK

4. Surgery Research Unit, University of Oulu and Oulu University Hospital , Oulu , Finland

5. School of Cancer and Pharmaceutical Sciences, King’s College London , London , UK

Abstract

Abstract Background It is unclear whether annual hospital volume of bariatric surgery influences the long-term survival of individuals who undergo surgery for severe obesity. The hypothesis that higher annual hospital volume of bariatric surgery is associated with better long-term survival was evaluated. Methods This retrospective population-based study included patients who underwent bariatric surgery in Sweden and Finland between 1989 and 2020. Annual hospital volume was analysed for risk of all-cause mortality. Multivariable Cox regression provided HRs with 95 per cent confidence intervals adjusted for age, sex, co-morbidity, country, and type of bariatric procedure. Results Weight loss surgery was performed in 77 870 patients with a 0.5 per cent risk of postoperative death (mortality rate (MR) per 100 000 people 592.7, 95 per cent c.i. 575.0 to 610.9). Higher annual hospital volume of bariatric surgery was associated with a lower risk of all-cause mortality. The adjusted HRs were slightly more reduced for each quartile of annual hospital volume compared with the lowest quartile (MR per 100 000 people for lowest quartile 815.1, 95 per cent c.i. 781.7 to 849.9; for quartile II: HR 0.88, 95 per cent c.i. 0.81 to 0.96 (MR per 100 000 people 545.0, 512.0 to 580.1); for quartile III: HR 0.87, 0.78 to 0.97 (MR per 100 000 people 428.8, 395.5 to 465.0); for quartile IV: HR 0.82, 0.73 to 0.93 (MR per 100 000 people 356.0, 324.1 to 391.1)). In analyses restricted to laparoscopic surgery, volume and mortality were related only in the crude model (HR 0.86, 0.75 to 0.98), but not in the multivariable model (HR 0.97, 0.84 to 1.13) that compared highest and lowest quartiles. Conclusion If there was a survival benefit associated with hospital volume, it may have been due to a faster uptake of laparoscopic surgery in the busier hospitals.

Funder

Swedish Research Council

Publisher

Oxford University Press (OUP)

Subject

Surgery

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