Joint contribution of MC1R and MITF alleles to melanoma risk in the age of polygenic risk scores
Author:
Affiliation:
1. Genetics of Rare Cancers, IRCCS Ospedale Policlinico San Martino , Largo Rosanna Benzi X, 16132 Genoa , Italy
2. Department of Internal Medicine and Medical Specialties (DiMI), University of Genoa , Viale Benedetto XV 6, 16132 Genoa , Italy
Publisher
Oxford University Press (OUP)
Subject
Dermatology
Link
https://academic.oup.com/bjd/advance-article-pdf/doi/10.1093/bjd/ljad097/50247820/ljad097.pdf
Reference9 articles.
1. Evolution of approaches to identify melanoma missing heritability;Dalmasso;Expert Rev Mol Diagn,2020
2. Multiplex melanoma families are enriched for polygenic risk;Law;Hum Mol Genet,2020
3. [Recommendations for genetic testing and management of individuals genetically at-risk of cutaneous melanoma];Avril;Ann Dermatol Venereol,2015
4. MITF–the first 25 years;Goding;Genes Dev,2019
5. Association of MC1R variants and host phenotypes with melanoma risk in CDKN2A mutation carriers: a GenoMEL study;Demenais;J Natl Cancer Inst,2010
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