Immune checkpoint inhibitor-induced bullous pemphigoid is characterized by interleukin (IL)-4 and IL-13 expression and responds to dupilumab treatment
Author:
Affiliation:
1. Departments of Dermatology
2. Pathology, Yale University School of Medicine , New Haven, CT , USA
Abstract
Funder
Colton Center for Autoimmunity at Yale
Publisher
Oxford University Press (OUP)
Subject
Dermatology
Link
https://academic.oup.com/bjd/advance-article-pdf/doi/10.1093/bjd/ljad149/50884476/ljad149.pdf
Reference8 articles.
1. Immune checkpoint blockade and skin toxicity pathogenesis;Ma;J Invest Dermatol,2022
2. Characterization of skin cytokines in bullous pemphigoid and pemphigus vulgaris;Rico;Br J Dermatol,1999
3. Skin-homing interleukin-4 and -13-producing cells contribute to bullous pemphigoid: remission of disease is associated with increased frequency of interleukin-10-producing cells;Teraki;J Invest Dermatol,2001
4. Dupilumab as a novel therapy for bullous pemphigoid: a multicenter case series;Abdat;J Am Acad Dermatol,2020
5. Dupilumab for the treatment of nivolumab-induced bullous pemphigoid: a case report and review of the literature;Klepper;Dermatol Online J,2021
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1. Safety of Immunomodulatory Systemic Therapies Used in the Management of Immune-Related Cutaneous Adverse Events;Pharmaceuticals;2023-11-15
2. Targeting interleukin (IL)-4/IL-13 in immune checkpoint inhibitor-induced bullous pemphigoid: a cautionary note on the beneficial effect of T helper 2 immunity in melanoma and immunotherapy: reply from the authors;British Journal of Dermatology;2023-11-08
3. Advancing Treatment in Bullous Pemphigoid: A Comprehensive Review of Novel Therapeutic Targets and Approaches;Clinical Reviews in Allergy & Immunology;2023-10-28
4. Targeting interleukin (IL)-4/IL-13 in immune checkpoint inhibitor-induced bullous pemphigoid: a cautionary note on the beneficial effect of T helper 2 immunity in melanoma and immunotherapy;British Journal of Dermatology;2023-09-13
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