Sleep problems, internalizing and externalizing symptoms, and domains of health-related quality of life: bidirectional associations from early childhood to early adolescence

Author:

Williamson Ariel A12ORCID,Zendarski Nardia3,Lange Katherine34,Quach Jon5,Molloy Carly34,Clifford Susan A34,Mulraney Melissa34ORCID

Affiliation:

1. Children’s Hospital of Philadelphia, Philadelphia, PA

2. Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

3. Population Health, Murdoch Children’s Research Institute, Parkville, Victoria, Australia

4. Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia

5. Melbourne Graduate School of Education, University of Melbourne, Carlton, Victoria, Australia

Abstract

Abstract Study Objectives To examine longitudinal, bidirectional associations among behavioral sleep problems, internalizing and externalizing symptoms, and domains of health-related quality of life (HRQoL) from early childhood to adolescence in a population sample of Australian children. Method Data were drawn from the Longitudinal Study of Australian Children, a national prospective cohort study with 4983 children participating in the Kindergarten cohort. Data were collected when children were aged 4–5, 6–7, 8–9, 10–11, and 12–13 years. At each study wave, the primary parent (97% mothers) reported on behavioral child sleep problems, internalizing and externalizing symptoms, and HRQoL domains (psychosocial and physical). Cross-lagged structural equation models were used to evaluate bidirectional associations. Results At nearly every age, behavioral sleep problems were associated with worse subsequent psychosocial and physical HRQoL. Despite bidirectional associations between mental health and HRQoL at many waves, HRQoL domains more strongly predicted later internalizing symptoms, while externalizing symptoms more strongly predicted later HRQoL. Many of the bidirectional associations among sleep, mental health, and HRQoL were found earlier in childhood. Conclusions Behavioral sleep problems may forecast later HRQoL psychosocial and physical impairments. Attending to both sleep problems and HRQoL could prevent the progression of internalizing conditions, while a focus on externalizing concerns could prevent the worsening of these symptoms, sleep problems, and HRQoL, particularly during the transition to school.

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Neurology (clinical)

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