Early detection of KP.2 SARS-CoV-2 variant using wastewater-based genomic surveillance in Pune, Maharashtra, India

Author:

Rajput Vinay123,Das Rashmita4,Pramanik Rinka123,Nannaware Kiran12,Yanamandra Sushma4,Taji Nyabom4,Rajput Vishal4,Rajkhowa Riyakshi4,Pacharne Poonam4,Shah Priyanki5,Gogate Niharika5,Sangwar Poornima5,Bhalerao Asim6,Jain Nidhi6,Kamble Sanjay7,Dastager Syed12,Shashidhara L S58,Karyakarte Rajesh4,Dharne Mahesh123ORCID

Affiliation:

1. National Collection of Industrial Microorganisms (NCIM) , Biochemical Sciences Division, , Pune 411008, Maharashtra, India

2. CSIR-National Chemical Laboratory (NCL) , Biochemical Sciences Division, , Pune 411008, Maharashtra, India

3. Academy of Scientific and Innovative Research (AcSIR) , Ghaziabad 201002, Uttar Pradesh, India

4. Department of Microbiology, Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals (BJGMC and SGH) , Jai Prakash Narayan Road, Pune 411001, Maharashtra, India

5. Pune Knowledge Cluster (PKC), Savitribai Phule Pune University (SPPU) , Pune 411007, Maharashtra, India

6. Fluid Robotics Private Limited (FRPL) , Pune 411052, Maharashtra, India

7. Chemical Engineering and Process Development (CEPD) Division, CSIR-National Chemical Laboratory , Pune 411008, Maharashtra, India

8. National Centre for Biological Sciences (NCBS), Tata Institute of Fundamental Research , Bellary Road, Bengaluru 560065, Karnataka, India

Abstract

Wastewater surveillance in Pune, India, detected KP.2 variant in December 2023, a month before its first global detection in clinical samples. The study highlights the critical role of wastewater-based surveillance for early detection of emerging variants, thus enhancing our ability in tackling public health threats effectively.

Funder

Rockefeller Foundation, USA

Publisher

Oxford University Press (OUP)

Reference7 articles.

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