Lack of a non-specific protective effect of prior yellow fever vaccination against COVID-19

Author:

Martínez-Lacalzada Miguel1,Cruz Angeline1,Subirà Carme1,Vera Isabel1,Roldan Montserrat1,De Alba Teresa1,Saloni Meritxell1,Muñoz Jose1,Rodríguez-Valero Natalia1

Affiliation:

1. Barcelona Institute for Global Health (ISGlobal), Hospital Clínic-Universitat de Barcelona , Roselló Street 132, 08036, Barcelona , Spain

Abstract

Live-attenuated virus vaccines, such as yellow fever vaccine, exhibit non-specific immunomodulatory effects, prompting exploration of their potential impact on COVID-19 pandemic. In this retrospective study, we didn’t observe an association between prior yellow fever vaccination with SARS-CoV-2 infection incidence. In the multivariate model, no association was found with COVID-19 prognosis.

Publisher

Oxford University Press (OUP)

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