Sirolimus: a new promising immunosuppressive drug. Towards a rationale for its use in renal transplantation
Author:
Affiliation:
1. Service de Transplantation, Hôpital Necker, Paris, France
Publisher
Oxford University Press (OUP)
Subject
Transplantation,Nephrology
Link
http://academic.oup.com/ndt/article-pdf/16/1/18/25041740/160018.pdf
Reference19 articles.
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2. Martel RR, Klicius J, Galet S. Inhibition of the immune response by rapamycin, a new antifungal antibiotic. Can J Physiol1977; 55: 48–51
3. Tanaka H, Kuroda A, Marusawa et al. Structure of FK 506: a novel immunosuppressant isolated from Streptomyces. J Am Chem Soc1987; 109: 5031–5033
4. Abraham RT, Wiederrecht GJ. Immunopharmacology of rapamycin. Annu Rev Immunol1996; 14: 483–510
5. Ryffel B, Weber E, Mihatsch MJ. Nephrotoxicity of immunosuppressants in rats: Comparison of macrolides with cyclosporin. Exp Nephrol1994; 2: 324–333
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