Long COVID among healthcare workers: a narrative review of definitions, prevalence, symptoms, risk factors and impacts

Author:

Dempsey Brendan1ORCID,Madan Ira2ORCID,Stevelink Sharon A M3ORCID,Lamb Danielle1ORCID

Affiliation:

1. Department of Primary Care and Population Health, University College London , 1-19 Torrington Place, London, WC1E 7HB , UK

2. Guy’s and St Thomas NHS Foundation Trust , St Thomas' Education Centre, 75-79 York Road, London, SE1 7NJ , UK

3. Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, 16 De Crespigny Park, King’s College London , London, SE5 8AF , UK

Abstract

Abstract Introduction Long COVID (LC) occurs when people experience symptoms for weeks, months or even years after a COVID-19 infection. This review looks at research exploring the LC definitions, prevalence, symptoms, risk factors, and associated impacts in research on healthcare workers (HCWs). Data sources We systematically searched five electronic databases (CINAHL, EMBASE, Medline, PsycInfo and PubMed) and compiled a narrative literature review based on 56 relevant studies. Areas of agreement LC is prevalent among HCWs who become infected by COVID-19. Many of the most frequent symptoms associated with LC in the general population are also reported among HCWs. Some risk factors for LC are also similar to those in the general population, such as female sex, older age, and having a pre-existing respiratory illness. Areas of controversy The mechanism(s) responsible for LC remains unknown. A variety of terms, timeframes and symptoms are used to define LC, creating difficulties in comparing results across studies. Much of the research is cross-sectional and fails to explore the impacts that prolonged symptoms have on HCWs’ personal and professional lives. Growing points The need to support HCWs with LC is clear. Identifying the mechanism(s) responsible for LC is a key priority, as this will inform treatments. Areas for developing research Future research should move towards a standard definition for LC. Greater attention should be paid to longitudinal and qualitative studies, which could give insights into prognosis, lived experience and work participation. Finally, studies evaluating treatments suitable for people with LC are timely.

Funder

National Institute for Health and Care Research

Maudsley NHS Foundation Trust

National Institute for Health and Care Research (NIHR) Maudsley Biomedical Research Centre

Colt Foundation

Publisher

Oxford University Press (OUP)

Reference87 articles.

1. A clinical case definition of post COVID-19 condition by a Delphi consensus, 6 October, 2021 [Internet];WHO;World Health Organization,2023

2. Long COVID: aiming for a consensus;Munblit;Lancet Respir Med,2022

3. Characterising long COVID: a living systematic review;Michelen;BMJ Glob Health,2021

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