Isocitrate Dehydrogenase Mutations in Low-Grade Gliomas Correlate With Prolonged Overall Survival in Older Patients

Author:

Jones Pamela S1,Carroll Kate T2,Koch Matthew1,DiCesare Jasmine A T3,Reitz Kara1,Frosch Matthew4,Barker Fred G1,Cahill Daniel P1,Curry William T1

Affiliation:

1. Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts

2. School of Medicine, University of California-San Diego, San Diego, California

3. Department of Neurosurgery, University of California-Los Angeles, Los Angeles, California

4. Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Clinical Neurology,Surgery

Reference34 articles.

1. Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas;Hartmann;Acta Neuropathol,2009

2. The 2016 world health organization classification of tumors of the central nervous system: a summary;Louis;Acta Neuropathol,2016

3. Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas;Cancer Genome Atlas Research Network;N Engl J Med,2015

4. Molecular genetics of low-grade gliomas: genomic alterations guiding diagnosis and therapeutic intervention. 11th Annual Frye-Halloran Brain Tumor Symposium;Jones;Neurosurg Focus,2013

5. Molecular features assisting in diagnosis, surgery, and treatment decision making in low-grade gliomas;Chen;Neurosurg Focus,2015

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