Impaired calcium homeostasis is associated with sudden cardiac death and arrhythmias in a genetic equivalent mouse model of the human HRC-Ser96Ala variant

Author:

Tzimas Christos1,Johnson Daniel M2,Santiago Demetrio J2,Vafiadaki Elizabeth1,Arvanitis Demetrios A1,Davos Constantinos H3,Varela Aimilia3,Athanasiadis Nikolaos C3,Dimitriou Constantinos3,Katsimpoulas Michalis3,Sonntag Stephan4,Kryzhanovska Mariya4,Shmerling Doron4,Lehnart Stephan E5,Sipido Karin R2,Kranias Evangelia G16,Sanoudou Despina17

Affiliation:

1. Department of Molecular Biology, Center of Basic Research, Biomedical Research Foundation, Academy of Athens, Soranou Efessiou 4, 115 27, Athens, Greece;

2. Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium;

3. Department of Clinical, Experimental Surgery and Translational Research Center, Biomedical Research Foundation, Academy of Athens, Athens, Greece;

4. PolyGene AG, Rümlang, Switzerland;

5. Department of Cardiology and Pulmonology, Heart Research Center Goettingen, University Medical Center Goettingen, Goettingen, Germany;

6. Department of Pharmacology and Cell Biophysics, College of Medicine, University of Cincinnati, Cincinnati, OH, USA;

7. 4th Department of Internal Medicine, Clinical Genomics and Pharmacogenomics Unit, Medical School, National and Kapodistrian University of Athens, Attikon University Hospital, Rimini 1, Chaidari 124 62, Greece

Publisher

Oxford University Press (OUP)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Physiology

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