Revisiting gametocyte biology in malaria parasites

Author:

Ngotho Priscilla1ORCID,Soares Alexandra Blancke1,Hentzschel Franziska1,Achcar Fiona1,Bertuccini Lucia2,Marti Matthias13ORCID

Affiliation:

1. Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, 120 University Road, Glasgow G12 8TA, UK

2. Core Facilities, Microscopy Area, Instituto Superiore di Sanita, Via Regina Elena 299, 00161 Rome, Italy

3. Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston 02115, MA, USA

Abstract

ABSTRACT Gametocytes are the only form of the malaria parasite that is transmissible to the mosquito vector. They are present at low levels in blood circulation and significant knowledge gaps exist in their biology. Recent reductions in the global malaria burden have brought the possibility of elimination and eradication, with renewed focus on malaria transmission biology as a basis for interventions. This review discusses recent insights into gametocyte biology in the major human malaria parasite, Plasmodium falciparum and related species.

Funder

European Research Council

DFG

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology

Reference130 articles.

1. Comparative fine structure study of the gametocytes of avian, reptilian, and mammalian malarial parasites;Aikawa;J Ultrastruct Res,1969

2. Caveola–vesicle complexes in the plasmalemma of erythrocytes infected by Plasmodium vivaxand P. cynomolgi. Unique structures related to Schuffner's dots;Aikawa;Am J Pathol,1975

3. Host cell deformability is linked to transmission in the human malaria parasite Plasmodium falciparum;Aingaran;Cell Microbiol,2012

4. Plasmodium falciparum: parasites defective in early stages of gametocytogenesis;Alano;Exp Parasitol,1995

5. PlasmoDB: a functional genomic database for malaria parasites;Aurrecoechea;Nucleic Acids Res,2009;

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3