Accuracy of human sperm DNA oxidation quantification and threshold determination using an 8-OHdG immuno-detection assay

Author:

Vorilhon S12,Brugnon F123,Kocer A2,Dollet S23,Bourgne C4,Berger M4,Janny L12,Pereira B5,Aitken R J6,Moazamian A7,Gharagozloo P7,Drevet J2,Pons-Rejraji H123

Affiliation:

1. CHU Clermont Ferrand, CHU Estaing, Laboratoire de Biologie du Développement et de la Reproduction, AMP, CECOS, F-63003 Clermont-Ferrand, France

2. Université Clermont Auvergne, CNRS UMR6293, INSERM U1103, GReD, F-63000 Clermont-Ferrand, France

3. Université Clermont Auvergne, UFR Médecine, INSERM 1240, IMoST., F-63000 Clermont-Ferrand, France

4. CHU Clermont Ferrand, Hôpital Estaing, Laboratoire d’Hématologie Biologique, F-63003 Clermont-Ferrand, France

5. CHU Clermont-Ferrand, DRCI, ‘Délégation Recherche Clinique et Innovation’, Clermont-Ferrand, France

6. Priority Research Centre in Reproductive Science, Discipline of Biological Sciences, University of Newcastle, Callaghan, NSW 2308, Australia

7. CellOxess LLC, 830 Bear Tavern Road, Ewing, NJ 08628, USA

Funder

Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale and Université Clermont Auvergne

Clermont-Ferrand Hospital-Centre d'Etude et de Conservation des Oeufs et du Sperme humains

Publisher

Oxford University Press (OUP)

Subject

Obstetrics and Gynecology,Rehabilitation,Reproductive Medicine

Reference47 articles.

1. The effect of sperm DNA damage on assisted reproduction outcomes. A review;Agarwal;Minerva Ginecol,2004

2. A free radical theory of male infertility;Aitken;Reprod Fertil Dev,1994

3. The Amoroso Lecture. The human spermatozoon – a cell in crisis?;Aitken;J Reprod Fertil,1999

4. Reactive oxygen species and sperm function—in sickness and in health;Aitken;J Androl,2012

5. Oxidative stress and male reproductive health;Aitken;Asian J Androl,2014

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