Protect us from poor-quality medical research

Author:

,Ioannidis John P A1,Bhattacharya Siladitya2,Evers J L H3,der Veen Fulco van4,Somigliana Edgardo5,Barratt Christopher L R6,Bontempi Gianluca7,Baird David T8,Crosignani PierGiorgio9,Devroey Paul10,Diedrich Klaus11,Farquharson Roy G12,Fraser Lynn R13,Geraedts Joep P M14,Gianaroli Luca15,La Vecchia Carlo16,Magli Cristina17,Negri Eva15,Sunde Arne18,Tapanainen Juha S19,Tarlatzis Basil C20,Steirteghem Andre Van21,Veiga Anna22

Affiliation:

1. Departments of Medicine, of Health Research and Policy, of Biomedical Data Science, and of Statistics, and Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, USA

2. Professor of Reproductive Medicine, Head of Division of Applied Health Sciences and Director Institute of Applied Health Sciences, School of Medicine and Dentistry, University of Aberdeen, Aberdeen Maternity Hospital, Foresterhill, Aberdeen, UK

3. Dept. Obstet. Gynecol., Maastricht University Medical Centre, Maastricht, The Netherlands

4. Academic Medical Centre, University of Amsterdam, Reproduction Medicine, Amsterdam, The Netherlands

5. Clinica Ostetrica e Ginecologica, IRCCS Ca’ Granda Foundation, Maggiore Policlinico Hospital, Milano, Italy

6. Division of Molecular & Clinical Medicine, School of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK

7. co-Head of the Machine Learning Group, Département d’Informatique, Université Libre de Bruxelles, Bruxelles, Belgium

8. Centre for Reproductive Biology, University of Edinburgh, UK

9. IRCCS Ca’ Granda Foundation, Maggiore Policlinico Hospital, Milano, Italy

10. AZ-VUB, Centre for Reproductive Medicine, Brussels, Belgium

11. Klin. Frauenheilkunde und Geburtshilfe, Univ. zu Lubeck, Lubeck, Germany

12. Liverpool Women’s Hospital, Department of OB/GYN, Liverpool, UK

13. Centre for Reproduction, Endocrinology & Diabetes, School of Biomedical Sciences, New Hunt’s House, Kings College London, Guy’s Campus, London, UK

14. AZ Maastricht, Klinische Genetica, Maastricht, The Netherlands

15. S.I.S.M.E.R., Bologna, Italy

16. Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milan, Italy

17. Reproductive Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden

18. Department of Biomedical and Clinical Sciences, Università degli Studi di Milano, Milano, Italy

19. University Hospital, Dept. Obstet. Gynecol., Trondheim, Norway

20. University of Helsinki, Department of Obstetrics and Gynecology, Helsinki University Hospital, University of Helsinki, Helsinki, Finland

21. Centre for Reproductive Medicine, Universitair Ziekenhuis Vrije Universiteit Brussel, Belgium

22. Reproductive Medicine Service, Dexeus Woemn’s Health, Barcelona, Spain

Funder

European Society of Human Reproduction and Embryology

Publisher

Oxford University Press (OUP)

Subject

Obstetrics and Gynecology,Rehabilitation,Reproductive Medicine

Reference49 articles.

1. The scandal of poor medical research;Altman;Br Med J,1994

2. Healthcare outcomes assessed with observational study designs compared with those assessed in randomized trials;Anglemyer;Cochrane Database Syst Rev,2014

3. Data resource profile: the Aberdeen Maternity and Neonatal Databank (AMND);Ayorinde;Int J Epidemiol,2016

4. Equipoise and the RCT;Braakhekke;Hum Reprod,2017

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