Fertility preservation before cancer treatment: the dilemma of saying ‘no’ as the price of glory

Author:

Grynberg Michaël12ORCID,Sermondade Nathalie34ORCID

Affiliation:

1. Department of Reproductive Medicine and Fertility Preservation, Hôpital Antoine Béclère, Hôpitaux Universitaires Paris Sud , Assistance Publique—Hôpitaux de Paris, Clamart, France

2. Université Paris-Sud, Université Paris Saclay , Le Kremlin Bicêtre, France

3. Department of Reproductive Biology, Hôpital Tenon , Assistance Publique—Hôpitaux de Paris, Paris, France

4. Centre de Recherche Saint Antoine, Sorbonne Universités, UPMC Université Paris 6, INSERM UMRS_938 , Paris, France

Abstract

Abstract A great deal of work has been carried out by professionals in reproductive medicine in order to raise awareness about fertility preservation (FP) techniques, particularly for women, and to ensure that FP is included in the care of young adults treated for cancer or a pathology requiring gonadotoxic treatment. If the importance of the development of our discipline is obvious, our militancy in favour of FP and our emotional projections must not make us forget that medical thinking must be carried out not only on a case-by-case basis, weighing up the benefit-risk balance, but also without losing sight that conceiving a child with one’s own gametes is not a vital issue. The cultural importance given to the genetic link with offspring may bias patients’ and physicians’ decisions, while other ways of achieving parenthood exist, and are often more effective. Systematic information should be provided on the existence of FP techniques, but this should not lead to their systematic implementation, nor should it obscure that early information will also allow patients to begin projecting themselves in alternative options to become parents.

Publisher

Oxford University Press (OUP)

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