A second dose of kisspeptin-54 improves oocyte maturation in women at high risk of ovarian hyperstimulation syndrome: a Phase 2 randomized controlled trial

Author:

Abbara Ali1,Clarke Sophie1,Islam Rumana2,Prague Julia K1,Comninos Alexander N1,Narayanaswamy Shakunthala1,Papadopoulou Deborah1,Roberts Rachel1,Izzi-Engbeaya Chioma1,Ratnasabapathy Risheka1,Nesbitt Alexander1,Vimalesvaran Sunitha1,Salim Rehan2,Lavery Stuart A2,Bloom Stephen R1,Huson Les3,Trew Geoffrey H2,Dhillo Waljit S1

Affiliation:

1. Department of Investigative Medicine, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK

2. IVF Unit, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK

3. Division of Experimental Medicine, Hammersmith Hospital, Du Cane Road, London, W12 0HS, UK

Funder

Medical Research Council (MRC)

Biotechnology and Bioscience Research Council (BBSRC)

National Institute for Health Research (NIHR)

NIHR/WellcomeTrust Imperial Clinical Research Facility and Imperial Biomedical Research Centre

NHS

NIHR Biomedical Research Centre Funding Scheme

National Institute of Health Research (NIHR) Clinical Lectureships

NIHR Research Professorship

NIHR Academic Clinical Fellowship and Imperial College Healthcare NHS trust Charity Fellowship

MRC Clinical Training Fellowship

Publisher

Oxford University Press (OUP)

Subject

Obstetrics and Gynaecology,Rehabilitation,Reproductive Medicine

Reference41 articles.

1. Efficacy of kisspeptin-54 to trigger oocyte maturation in women at high risk of ovarian hyperstimulation syndrome (OHSS) during in vitro fertilization (IVF) therapy;Abbara;J Clin Endocrinol Metab,2015

2. The Effects of Kisspeptin on Gonadotropin Release in Non-human Mammals

3. Assisted reproductive technology in Europe, 2012: results generated from European registers by ESHRE;Calhaz-Jorge;Hum Reprod Adv Access Publ [Internet],2016

4. Kisspeptin synchronizes preovulatory surges in cyclical ewes and causes ovulation in seasonally acyclic ewes;Caraty;Endocrinology,2007

5. Pharmaceutical options for triggering of final oocyte maturation in ART;Castillo;Biomed Res Int,2014

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