Genome stability of bovine in vivo-conceived cleavage-stage embryos is higher compared to in vitro-produced embryos

Author:

Tšuiko Olga1234,Catteeuw Maaike5,Zamani Esteki Masoud6,Destouni Aspasia1,Bogado Pascottini Osvaldo5,Besenfelder Urban7,Havlicek Vitezslav7,Smits Katrien5,Kurg Ants4,Salumets Andres2389,D’Hooghe Thomas10,Voet Thierry611,Van Soom Ann5,Robert Vermeesch Joris1

Affiliation:

1. Laboratory of Cytogenetics and Genome Research, Center of Human Genetics, KU Leuven, Leuven 3000, Belgium

2. Institute of Bio- and Translational Medicine, University of Tartu, Tartu 50411, Estonia

3. Competence Centre on Health Technologies, Tartu 50410, Estonia

4. Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu, Tartu 51010, Estonia

5. Department of Obstetrics, Reproduction and Herd Health, Ghent University, Merelbeke 9820, Belgium

6. Laboratory of Reproductive Genomics, Center of Human Genetics, KU Leuven, Leuven 3000, Belgium

7. Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna 1210, Austria

8. Department of Obstetrics and Gynaecology, Institute of Clinical Medicine, University of Tartu, Tartu 51014, Estonia

9. Department of Obstetrics and Gynaecology, University of Helsinki and Helsinki University Hospital, Helsinki 00029, Finland

10. Department of Obstetrics and Gynaecology, Leuven University Fertility Centre, University Hospital Leuven, Leuven 3000, Belgium

11. Sanger-EBI Single Cell Genomics Centre, Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1SA, UK

Funder

Agency for Innovation by Science and Technology

Research Foundation Flanders

European Union's FP7 Marie Curie Industry-Academia Partnerships and Pathways

Horizon 2020 innovation programme

Estonian Ministry of Education and Research

Publisher

Oxford University Press (OUP)

Subject

Obstetrics and Gynecology,Rehabilitation,Reproductive Medicine

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