Recombinant human granulocyte– colony stimulating factor in women with unexplained recurrent pregnancy losses: a randomized clinical trial

Author:

Eapen A12ORCID,Joing M3,Kwon P3,Tong J3,Maneta E1,De Santo C1,Mussai F1,Lissauer D1,Carter D3,Eapen A4,Joing M5,Kwon P5,Tong J5,Carter D5,Maneta E1,De Santo C1,Mussai F1,Ahmed A6,Bass C7,Bender-Atik R8,Bhattacharya R9,Cheong Y10,Dawood F11,Granne I12,Gupta P13,Horne A14,Manda P15,Mohiyiddeen L16,Moore J17,Quenby S18,Rai R19,Shillito J20,Stewart J21,Truchanowicz E22,Dwyer L16,Small R13,Sharpe L23,Smith A11,Lissauer D1,Coomarasamy A1,

Affiliation:

1. Tommy’s National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, University of Birmingham, UK

2. University of Iowa Hospitals and Clinics, Carver college of Medicine, IA, USA

3. Nora Therapeutics, Inc., 530 Lytton Avenue, 2nd Floor, Palo Alto, CA, USA

4. Tommy’s National Centre for Miscarriage Research, Institute of Metabolism and Systems Research, University of Birmingham, UK & University of Iowa Hospitals and Clinics, Carver college of Medicine, Iowa, USA

5. Nora Therapeutics, California, USA

6. Sunderland Royal Hospital, Sunderland, UK

7. St. Peters Hospital, Ashford, UK

8. Miscarriage Association, UK

9. Derriford Hospital, Plymouth, UK

10. University of Southampton, UK

11. Liverpool Women’s Hospital, UK

12. University of Oxford, UK

13. Birmingham Heartlands Hospital, UK

14. MRC Centre for Reproductive Health, Edinburgh, UK

15. James Cook University Hospital, Middlesborough, UK

16. St Mary’s Hospital, Manchester, UK

17. Queens Medical Centre, Nottingham, UK

18. University Hospital, Coventry, UK

19. St Mary’s Hospital, London, UK

20. St James’ Hospital, Leeds, UK

21. Royal Victoria Infirmary, Newcastle upon Tyne, UK

22. Alta Innovations Ltd, UK

23. St. Peters Hospital, Ashford

Funder

Nora Therapeutics, Inc

Publisher

Oxford University Press (OUP)

Subject

Obstetrics and Gynaecology,Rehabilitation,Reproductive Medicine

Reference21 articles.

1. Colony-stimulating factors for febrile neutropenia;Carton;N Engl J Med,2013

2. Risk factors associated with a new pregnancy loss and perinatal outcomes in cases of recurrent miscarriage treated with lymphocyte immunotherapy;Cavalcante;J Matern Fetal Neonatal Med,2014

3. Granulocyte colony-stimulating factor and reproductive medicine: A review;Cavalcante;Iran J Reprod Med,2015

4. Should anti-TNF-alpha therapy be offered to patients with infertility and recurrent spontaneous abortion?;Clark;Am J Reprod Immunol,2009

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