1. Department of Human Genetics, 1241 East Catherine Street, University of Michigan, Ann Arbor, MI 48109-0618, USA
2. Present address: Department of Mathematics and Statistics, University of Canterbury, Private Bag 4800, Christchurch 8140, New Zealand
3. Center for Computational Medicine and Biology, 2017 Palmer Commons, 100 Washtenaw Avenue, University of Michigan, Ann Arbor, MI 48109-2218, USA
4. Department of Mathematics, University of Auckland, Private Bag 29019, Auckland, New Zealand