Patient and Provider Acceptability of a Patient Preauthorized Concealed Opioid Reduction

Author:

Bedford Theresa1,Adediran Timileyin2,Haycock Nathaniel R3,Mullins C Daniel4ORCID,Medeiros Michelle4,Wright Thelma5,Curatolo Michele6ORCID,Hamlin Lynette1ORCID,Colloca Luana357ORCID

Affiliation:

1. Uniformed Services University of the Health Sciences, Graduate School of Nursing, Bethesda, Maryland, USA

2. Department of Epidemiology and Human Genetics, School of Medicine, University of Maryland, Baltimore, Maryland, USA

3. Department of Pain and Translational Symptom Science, School of Nursing, University of Maryland, Baltimore, Maryland, USA

4. School of Pharmacy, University of Maryland, Baltimore, Maryland, USA

5. Department of Anesthesiology, School of Nursing, University of Maryland, Baltimore, Maryland, USA

6. Department of Anesthesiology & Pain Medicine, University of Washington, School of Medicine, Seattle, USA

7. Center to Advance Chronic Pain Research, University of Maryland, Baltimore, Maryland USA

Abstract

Abstract Objective Limited research of how to best taper opioids brings about an ethical and clinical dilemma. Experiments using overt and concealed administration of opioids have demonstrated the benefits of a concealed reduction to eliminate negative expectations and prolong analgesic benefits. This may allow for opioid tapering without significant increases in pain. Based on this, we investigated patient and provider acceptance of a concealed opioid reduction for chronic pain. Methods We conducted a cross-sectional survey via REDcap with 74 patients, who are currently taking or have taken high dose opioids, and 49 providers using a validated questionnaire based on two hypothetical clinical trials comparing a patient preauthorized concealed opioid reduction vs standard tapering. Results We found that patients and providers have positive attitudes toward a concealed reduction of opioid dosages. More than 60% of providers and patients surveyed viewed the hypothetical clinical trial as helpful to reduce pain, side effects, and withdrawal symptoms. Sixty-one percent of patients and 77.6% of providers recognized that there would be differences in pain relief depending upon which group the hypothetical participants would be enrolled in. Conclusions Patients and providers appear to understand the benefits of a concealed opioid reduction. Our findings support future randomized controlled trials that compare concealed and overt opioid tapering in patients with chronic pain. More research is needed to understand the difference in attitudes between research and clinical practice and to test the acceptability of a concealed reduction following a participation in an active clinical trial.

Funder

Agency for Healthcare Research and Quality

MPowering the State: Strategic Partnership Grant

Maryland Center for Addiction Research, Education, and Service

Publisher

Oxford University Press (OUP)

Subject

Anesthesiology and Pain Medicine,Clinical Neurology,General Medicine

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