Redistribution of garbage codes to underlying causes of death: a systematic analysis on Italy and a comparison with most populous Western European countries based on the Global Burden of Disease Study 2019

Author:

Monasta Lorenzo1ORCID,Alicandro Gianfranco23,Pasovic Maja4,Cunningham Matthew4,Armocida Benedetta1,Ronfani Luca1,Naghavi Mohsen4,Monasta Lorenzo,Alicandro Gianfranco,Pasovic Maja,Cunningham Matthew,Armocida Benedetta,Albano Luciana,Beghi Ettore,Beghi Massimiliano,Bosetti Cristina,Bragazzi Nicola Luigi,Carreras Giulia,Castelpietra Giulio,Catapano Alberico L,Cattaruzza Maria Sofia,Collatuzzo Giulia,Conti Sara,Damiani Giovanni,Ferrara Pietro,Fornari Carla,Gallus Silvano,Giampaoli Simona,Golinelli Davide,Isola Gaetano,Lauriola Paolo,La Vecchia Carlo,Leonardi Matilde,Magnani Francesca Giulia,Minelli Giada,Moccia Marcello,Pedersini Paolo,Perico Norberto,Raggi Alberto,Remuzzi Giuseppe,Sanmarchi Francesco,Sattin Davide,Unim Brigid,Villafañe Jorge Hugo,Violante Francesco S,Murray Christopher J L,Ronfani Luca,Naghavi Mohsen,

Affiliation:

1. Institute for Maternal and Child Health–IRCCS “Burlo Garofolo”, Trieste, Italy

2. Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy

3. Cystic Fibrosis Center, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

4. Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA

Abstract

Abstract Background The proportion of reported causes of death (CoDs) that are not underlying causes can be relevant even in high-income countries and seriously affect health planning. The Global Burden of Disease (GBD) study identifies these ‘garbage codes’ (GCs) and redistributes them to underlying causes using evidence-based algorithms. Planners relying on vital registration data will find discrepancies with GBD estimates. We analyse these discrepancies, through the analysis of GCs and their redistribution. Methods We explored the case of Italy, at national and regional level, and compared it to nine other Western European countries with similar population sizes. We analysed differences between official data and GBD 2019 estimates, for the period 1990–2017 for which we had vital registration data for most select countries. Results In Italy, in 2017, 33 000 deaths were attributed to unspecified type of stroke and 15 000 to unspecified type of diabetes, these making a fourth of the overall garbage. Significant heterogeneity exists on the overall proportion of GCs, type (unspecified or impossible underlying causes), and size of specific GCs among regions in Italy, and among the select countries. We found no pattern between level of garbage and relevance of specific GCs. Even locations performing below average show interesting lower levels for certain GCs if compared to better performing countries. Conclusions This systematic analysis suggests the heterogeneity in GC levels and causes, paired with a more detailed analysis of local practices, strengths and weaknesses, could be a positive element in a strategy for the reduction of GCs in Italy.

Funder

Bill & Melinda Gates Foundation

Publisher

Oxford University Press (OUP)

Subject

Public Health, Environmental and Occupational Health

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4. Reliability of causes-of-death statistics: the Italian experience from the ICD-10 training course;Grippo;Rivista di Statistica Ufficiale,2015

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