Targeting of 5-aza-2′-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme
Author:
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
http://academic.oup.com/nar/article-pdf/38/13/4313/16766230/gkq187.pdf
Reference22 articles.
1. Mechanism of action of eukaryotic DNA methyltransferase. Use of 5-azacytosine-containing DNA;Taylor;J. Mol. Biol.,1982
2. Kinetic and catalytic mechanism of HhaI methyltransferase;Wu;J. Biol. Chem.,1987
3. Trapped in action: direct visualization of DNA methyltransferase activity in living cells;Schermelleh;Nat. Methods,2005
4. 5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signal;Ghoshal;Mol. Cell. Biol.,2005
5. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development;Okano;Cell,1999
Cited by 151 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Inhibition of TOPORS ubiquitin ligase augments the efficacy of DNA hypomethylating agents through DNMT1 stabilization;Nature Communications;2024-08-28
2. Cytosine analogues as DNA methyltransferase substrates;Nucleic Acids Research;2024-07-05
3. Triptolide sensitizes cancer cells to nucleoside DNA methyltransferase inhibitors through inhibition of DCTPP1-mediated cell-intrinsic resistance;2024-05-21
4. Decitabine cytotoxicity is promoted by dCMP deaminase DCTD and mitigated by SUMO-dependent E3 ligase TOPORS;The EMBO Journal;2024-05-17
5. Mouse Embryonic Stem Cells Require Sustained DNMT1-Mediated DNA Methylation Maintenance for Epigenomic, Genomic and Functional Integrity;2024-05-10
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3