Driving forces for natural soil salinity and alkalinity are climate, rock weathering, ion exchange, and mineral equilibria reactions that ultimately control the chemical composition of soil and water. The major weathering reactions that produce soluble ions are tabled. Where evapotranspiration is greater than precipitation, downward water movement is insufficient to leach solutes out of the soil profile and salts can precipitate. Microbes involved in organic matter mineralization and thus the carbon, nitrogen, and sulfur biogeochemical cycles are also implicated. Seasonal contrast and evaporative concentration during dry periods accelerate short-term oxidation-reduction reactions and local and regional accumulation of carbonate and sulfur minerals. The presence of salts and alkaline conditions, together with the occurrence of drought and seasonal waterlogging, creates some of the most extreme soil environments where only specially adapted organisms are able to survive. Sodic soils are alkaline, rich in sodium carbonates, with an exchange complex dominated by sodium ions. Such sodic soils, when low in other salts, exhibit dispersive behavior, and they are difficult to manage for cropping. Maintaining the productivity of sodic soils requires control of the flocculation-dispersion behavior of the soil. Poor land management can also lead to anthropogenically induced secondary salinity. New developments in physical chemistry are providing insights into ion exchange and how it controls flocculation-dispersion in soil. New water and solute transport models are enabling better options of remediation of saline and/or sodic soils.