Pharmacists’ role in detection and evaluation of adverse drug reactions: Developing proactive systems for pharmacosurveillance

Author:

Salazar Alejandra1,Amato Mary G2,Shah Sonam N3,Khazen Maram45,Aminmozaffari Saina6,Klinger Elissa V7,Volk Lynn A8,Mirica Maria6,Schiff Gordon D9

Affiliation:

1. Division of General Internal Medicine, Brigham and Women’s Hospital, Boston, MA, and Boston Medical Center , Boston, MA , USA

2. Division of General Internal Medicine, Brigham and Women’s Hospital, Boston, MA, and MCPH University , Boston, MA , USA

3. Division of General Internal Medicine, Brigham and Women’s Hospital, Boston, MA, and Dana Farber Cancer Institute , Boston, MA , USA

4. School of Public Health, Haifa University , Haifa , Israel

5. Nursing School, Zefat Academic College , Zefat , Israel

6. Division of General Internal Medicine, Brigham and Women’s Hospital , Boston, MA , USA

7. Penn Medicine Center for Digital Health, Philadelphia, PA, and Penn Medicine Center for Health Care Innovation , Philadelphia, PA , USA

8. Mass General Brigham , Somerville, MA , USA

9. Division of General Internal Medicine, Brigham and Women’s Hospital, Boston, MA, and Harvard Medical School , Boston, MA , USA

Abstract

AbstractPurposeTo identify current challenges in detection of medication-related symptoms, and review technology-based opportunities to increase the patient-centeredness of postmarketing pharmacosurveillance to promote more accountable, safer, patient-friendly, and equitable medication prescribing.SummaryPharmacists have an important role to play in detection and evaluation of adverse drug reactions (ADRs). The pharmacist’s role in medication management should extend beyond simply dispensing drugs, and this article delineates the rationale and proactive approaches for pharmacist detection and assessment of ADRs. We describe a stepwise approach for assessment, best practices, and lessons learned from a pharmacist-led randomized trial, the CEDAR (Calling for Detection of Adverse Drug Reactions) project.ConclusionHealth systems need to be redesigned to more fully utilize health information technologies and pharmacists in detecting and responding to ADRs.

Funder

Gordon and Betty Moore Foundation

Publisher

Oxford University Press (OUP)

Subject

Health Policy,Pharmacology

Reference38 articles.

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