Crohn Disease and Fracture Risk Assessment With FRAX-Reference-Cited by-同舟云学术

Crohn Disease and Fracture Risk Assessment With FRAX

Published:2019-07-01 Issue:2 Volume:1 Page:
ISSN:2631-827X
Container-title:Crohn's & Colitis 360
language:en
Short-container-title:

Author:

Jonasson Grethe B¹²^ORCID,Hilon Jack²,Hasseus Bengt³,Alstad Torgny⁴,Kashani Hossein⁵

Affiliation:

1. Department of Behavioral and Community Dentistry, Institute of Odontology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

2. Research and Development Unit in Southern Alvsborg County, Boras, Sweden

3. §Department of Oral Medicine and Pathology, Institute of Odontology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

4. ¶Department of Prosthodontics and Dental Material Science, Institute of Odontology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

5. Department of Oral and Maxillofacial Surgery, Institute of Odontology at the Sahlgrenska Academy, University of Gothenburg, Gothenburg Sweden

Abstract

Abstract Background Studies are inconsistent whether people with Crohn disease (CD) have an increased fracture risk. This study showed that patients with Crohn’s disease (CD) had a higher ten year probability of fracture, assessed by the fracture assessment tool FRAX, and more fractures, but the proportion of CD patients with a fracture was not significantly higher than that of controls. Methods Forty-nine CD and 49 controls participated. All 98 completed a health questionnaire. A score with the fracture assessment tool FRAX > 15% was considered risk factor for fracture. Results Mean FRAX score for 49 CD was 10.1 ± 10.3% and for 49 controls 5.0 ± 3.9% (P = 0.002). The variables correlated with fracture were being female (P = 0.04) and having a fractured mother (P = 0.002). Conclusion The CD group had significantly higher FRAX scores and more fractures, but the proportion of CD subjects with a fracture was not significantly higher than that of controls.

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology

Link

http://academic.oup.com/crohnscolitis360/advance-article-pdf/doi/10.1093/crocol/otz023/29105546/otz023.pdf

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