Reclassifying Pseudopolyps in Inflammatory Bowel Disease: Histologic and Endoscopic Description in the New Era of Mucosal Healing-Reference-Cited by-同舟云学术

Reclassifying Pseudopolyps in Inflammatory Bowel Disease: Histologic and Endoscopic Description in the New Era of Mucosal Healing

Published:2019-10-01 Issue:3 Volume:1 Page:
ISSN:2631-827X
Container-title:Crohn's & Colitis 360
language:en
Short-container-title:

Author:

Rezapour Mona¹,Quintero Maria Alejandra²,Khakoo Nidah S³,Sussman Daniel A²,Barkin Jodie A²,Clarke Jennifer⁴,Varma Tanya⁵,Deshpande Amar R²,Kerman David H²,Damas Oriana²,Abreu Maria T²

Affiliation:

1. Department of Gastroenterology and Hepatology, University of California Los Angeles, Los Angeles, California

2. Department of Gastroenterology and Hepatology, University of Miami, Miami, Florida

3. Department of Medicine, University of Miami, Miami, Florida

4. Nebraska Food for Health Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska

5. Ameripath, Shreveport, Louisiana

Abstract

Abstract Introduction In this study, we identify the frequency of pseudopolyps (PPs) with normal histology and their association to surrounding tissue. Methods Patients were enrolled in a study identifying endoscopic characteristics of PPs (n = 29) or were collected as part of our IBD biobank (n = 16). Statistical analysis included Stata v.15.0. chi-square and Student t-test. Results A total of 45 patients with 117 PP biopsies were identified. More patients with healed PP were in endoscopic remission compared with those with inflammatory PP (82.6% vs 17.4%, respectively). Conclusion This is the first study to find mucosal healing of PPs and its association with deep remission.

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology

Link

http://academic.oup.com/crohnscolitis360/article-pdf/1/3/otz033/33031065/otz033.pdf

Reference24 articles.

1. Inflammatory bowel disease: clinical aspects and established and evolving therapies;Baumgart;Lancet.,2007

2. SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease;Laine;Gastroenterology.,2015

3. Most dysplasia in ulcerative colitis is visible at colonoscopy;Rutter;Gastrointest Endosc.,2004