Prevalence Rates of Pneumococcal Vaccination in IBD and 30-Day Clinical Outcomes in Patients With IBD and Pneumococcal Disease Stratified by Receipt of Pneumococcal Vaccination: A Multi-Network Study

Author:

Ford Andrew1ORCID,Chittajallu Vibhu2,Abraham Perez Jaime3,Martin Scott3,Alkhayyat Motasem4,Dave Maneesh5ORCID,Ho Edith Y6,Sinh Preetika7ORCID,Nguyen Vu2,Cooper Gregory2,Katz Jeffry2,Cominelli Fabio2ORCID,Regueiro Miguel4ORCID,Mansoor Emad2

Affiliation:

1. Department of Internal Medicine, Cleveland Clinic Foundation , Cleveland, OH , USA

2. Digestive Health Institute, Case Western Reserve University/University Hospitals Cleveland Medical Center , Cleveland, OH , USA

3. Clinical Research Center, University Hospitals Cleveland Medical Center , Cleveland, OH , USA

4. Department of Gastroenterology, Hepatology, and Nutrition, Digestive Disease and Surgery Institute, Cleveland Clinic Foundation , Cleveland, OH , USA

5. Division of Gastroenterology and Hepatology, Department of Internal Medicine, UC Davis Medical Center, UC Davis School of Medicine , Sacramento, CA , USA

6. Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine , Stanford, CA , USA

7. Division of Gastroenterology and Hepatology, Medical College of Wisconsin , Milwaukee, WI , USA

Abstract

Lay Summary This study sought to assess outcomes associated with pneumococcal vaccination in adult inflammatory bowel disease patients. Results found unvaccinated patients had higher adverse outcomes, including greater risk of hospitalization, ICU admission, ventilation, and mortality. These findings underscore the importance of pneumococcal vaccination.

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology

Reference14 articles.

1. Increased risk of pneumonia among patients with inflammatory bowel disease;Long;Am J Gastroenterol.,2013

2. Inflammatory bowel disease patients are at increased risk of invasive pneumococcal disease: a nationwide Danish cohort study 1973-2013;Kantso;Am J Gastroenterol.,2015

3. ACG clinical guideline: preventative care in inflammatory bowel disease;Farraye;Am J Gastroenterol.,2017

4. Vaccinating patients with inflammatory bowel disease;Reich;Gastroenterol Hepatol (NY),2016

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