Is Occupation a Risk Factor for Developing Inflammatory Bowel Disease? A Case–Control Study

Author:

Mauriz-Barreiro Violeta12ORCID,Ruano-Raviña Alberto34,Ferreiro-Iglesias Rocío5,Bastón-Rey Iria5,Calviño-Suárez Cristina5,Nieto-García Laura5,Porto-Silva Sol5,Martínez-Seara Xurxo5,Domínguez-Munoz J Enrique5,Barreiro-de Acosta Manuel25ORCID

Affiliation:

1. Gastroenterology Department, Clinical University Hospital of Ferrol , Ferrol , Spain

2. University of Santiago de Compostela , Santiago de Compostela , Spain

3. Department of Preventive Medicine and Public Health, University of Santiago de Compostela , Santiago de Compostela , Spain

4. CIBER de Epidemiología y Salud Pública (CIBERESP) , Madrid , Spain

5. Clinical University Hospital of Santiago de Compostela , Santiago de Compostela , Spain

Abstract

Abstract Background and aims The role of occupation is uncertain in the onset of inflammatory bowel diseases. The aim of this study is to identify if there is a role of occupation in these diseases. Materials and methods A case–control study with incident cases with inflammatory bowel diseases was designed. Cases and controls were recruited simultaneously and controls followed a sex and age frequency matching with cases. A detailed questionnaire was completed by all the participants. To analyze the results, a logistic regression was used. A subgroup analysis was performed for each inflammatory bowel disease. Results A total of 141 patients with incident inflammatory bowel disease (80 ulcerative colitis, 55 Crohn’s disease, and 6 unclassified colitis) and 114 controls were included. There were no statistically significant differences in type of work, working hours, contact with animals, or physical activity at work between inflammatory bowel disease patients and controls. After stratifying results according to type of IBD, there were no statistically significant differences either. Conclusions There seems to be no risk for inflammatory bowel disease onset regarding the type of work, working hours, contact with animals, or sedentariness.

Funder

Janssen-Antonio Obrador GETECCU

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology

Reference26 articles.

1. Inflammatory bowel disease: historical perspective, epidemiology, and risk factors;Malik,2015

2. Confirming complexity: assessing environmental and genetic risk factors for inflammatory bowel disease;Friedman,2019

3. Environmental risk factors for inflammatory bowel disease;Molodecky;Gastroenterol Hepatol (N Y),2010

4. Geographical variability and environmental risk factors in inflammatory bowel disease;Ng,2013

5. Risk factors for inflammatory bowel disease: a prospective multi-center study;Amarapurkar,2018

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