Usefulness of Procalcitonin in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis-Reference-Cited by-同舟云学术

Usefulness of Procalcitonin in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis

Published:2019-09-12 Issue:3 Volume:1 Page:
ISSN:2631-827X
Container-title:Crohn's & Colitis 360
language:en
Short-container-title:

Author:

Cheung Donna Ann¹^ORCID,Tamariz Leonardo²,Nemeth Zsuzsanna³,Langshaw Amber Hamid⁴

Affiliation:

1. Division of Pediatric Gastroenterology, Hepatology, Pancreatology and Nutrition, Stead Family Department of Pediatrics, University of Iowa, Iowa City, IA

2. Division of Population Health and Computational Medicine, Department of Medicine, University of Miami, Miami, FL

3. Department of Health Informatics, Leonard M. Miller School of Medicine, University of Miami, Miami, FL

4. Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Miami, Miami, FL

Abstract

Abstract Background Mixed results are reported for procalcitonin (PCT) as biomarkers of infection and disease activity in inflammatory bowel disease (IBD). Method We systematically evaluated and performed a meta-analysis on the usefulness of PCT in assessing infection and disease activity in IBD. Results The pooled standardized mean difference of PCT for those with infection compared with those without was 1.59 (95% CI, 0.72–2.46, P < 0.01) and those with active disease compared with those without was 1.22 (95% CI, 0.66–1.78, P < 0.01), respectively. Conclusion PCT may potentially be useful in differentiating an infectious process from IBD and active from inactive IBD.

Publisher

Oxford University Press (OUP)

Subject

General Earth and Planetary Sciences,General Engineering,General Environmental Science

Link

http://academic.oup.com/crohnscolitis360/advance-article-pdf/doi/10.1093/crocol/otz032/30041316/otz032.pdf

Reference22 articles.

1. Update on procalcitonin measurements;Meisner;Ann Lab Med.,2014

2. Diagnostic accuracies of procalcitonin and C-reactive protein for bacterial infection in patients with systemic rheumatic diseases: a meta-analysis;Song;Clin Exp Rheumatol.,2015

3. Noninvasive tests for inflammatory bowel disease: a meta-analysis;Holtman;Pediatrics,2016

4. C-Reactive protein, fecal calprotectin, and stool lactoferrin for detection of endoscopic activity in symptomatic inflammatory bowel disease patients: a systematic review and meta-analysis;Mosli;Am J Gastroenterol.,2015

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Procalcitonin in inflammatory bowel disease: A diagnostic or prognostic marker;Pathology - Research and Practice;2024-10

2. Common and Novel Markers for Measuring Inflammation and Oxidative Stress Ex Vivo in Research and Clinical Practice—Which to Use Regarding Disease Outcomes?;Antioxidants;2021-03-09