Severe drug-induced liver injury (DILI) associated with benznidazole therapy for Chagas’ disease

Author:

Giancola Maria Letizia1,Corpolongo Angela1ORCID,Comandini Ubaldo Visco1,del Nonno Franca1,Montalbano Marzia1,Petrone Ada1,Carrara Stefania1,Mariano Andrea1,Beccacece Alessia1,Maffongelli Gaetano1,Nicastri Emanuele1

Affiliation:

1. Clinical Department, National Institute for Infectious Diseases ‘Lazzaro Spallanzani’ , IRCCS-Via Portuense, 292 , Italy

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

Reference10 articles.

1. Trypanocidal drugs for late-stage, symptomatic Chagas disease (Trypanosoma cruzi infection);Vallejo;Cochrane Database Syst Rev,2020

2. Pharmacokinetics and tissue distribution of benznidazole after oral administration in mice;Perin;Antimicrob Agents Chemother,2017

3. Clinical and pharmacological profile of benznidazole for treatment of Chagas disease;Kratz;Expert Rev Clin Pharmacol,2018

4. Toxic profile of benznidazole in patients with chronic Chagas disease: risk factors and comparison of the product from two different manufacturers;Molina;Antimicrob Agents Chemother,2015

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1. Various drugs;Reactions Weekly;2023-07-08

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