Human immunodeficiency virus infection is associated with a differential increase in cytokine response and increased risk of perforation in acute appendicitis-Reference-Cited by-同舟云学术

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Human immunodeficiency virus infection is associated with a differential increase in cytokine response and increased risk of perforation in acute appendicitis

Published:2021-03-31 Issue:5 Volume:108 Page:463-468
ISSN:0007-1323
Container-title:British Journal of Surgery
language:en
Short-container-title:

Author:

Wheeler N¹,Steel H C²,Setlai B D P¹,Meintjes F¹,Mokoena T¹^ORCID

Affiliation:

1. Department of Surgery, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa

2. Department of Immunology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa

Abstract

HIV infection causes increased perforation rate in acute appendicitis and alters cytokine profile resulting in increased pro-inflammatory cytokines in serum but decreased in peritoneal fluid. It is also accompanied by increased anti-inflammatory cytokines.

Funder

Institute of Biostatistics of the South African Medical Research Council

Publisher

Oxford University Press (OUP)

Subject

Surgery

Link

https://academic.oup.com/bjs/article-pdf/108/5/463/41930776/znaa170.pdf

Reference20 articles.

1. The global incidence of appendicitis: a systematic review of population-based studies;Ferris;Ann Surg,2017

2. Acute appendicitis in a developing country;Kong;World J Surg,2012

3. Regional and systemic cytokine responses to acute inflammation of the vermiform appendix;Rivera-Chavez;Ann Surg,2003

4. Human cytokine levels in nonperforated versus perforated appendicitis: molecular serum markers for extent of disease?;Yoon;Am Surg,2002

5. Possible cytokine biomarkers in pediatric acute appendicitis;Stankovic;Ital J Pediatr,2019

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