Affiliation:
1. Bayer AG, Pharma Research Centre, PO Box 101709, 42096 Wuppertal, Germany
Abstract
Abstract
The in-vitro activities of moxifloxacin, ciprofloxacin, erythromycin and rifampicin against 49 Legionella spp. isolates were determined by an agar dilution method with buffered charcoal yeast extract agar containing α-ketoglutarate. Because the inhibitory effects of charcoal in the test media were pronounced (92% for quinolones, 90.5% for rifampicin and 92.5% for erythromycin), the MICs were corrected for the charcoal-bound fraction of the antibiotics. The corrected geometric mean MICs were 0.018 mg/L for moxifloxacin, 0.02 mg/L for ciprofloxacin, 0.27 mg/L for erythromycin and 0.005 mg/L for rifampicin.
Publisher
Oxford University Press (OUP)
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)
Cited by
20 articles.
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