Detection of Albumin Expression by RNA In Situ Hybridization Is a Sensitive and Specific Method for Identification of Hepatocellular Carcinomas and Intrahepatic Cholangiocarcinomas

Author:

Lin Fan1,Shi Jianhui1,Wang Hanlin L2,Ma Xiao-Jun3,Monroe Robert3,Luo Yuling3,Chen Zongming1,Liu Haiyan1

Affiliation:

1. Geisinger Medical Center, Danville, PA

2. Department of Pathology and Laboratory Medicine, University of California Los Angeles, Los Angeles

3. Advanced Cell Diagnostics, Hayward, CA

Publisher

Oxford University Press (OUP)

Subject

General Medicine

Reference32 articles.

1. Branched chain in situ hybridization for albumin as a marker of hepatocellular differentiation: evaluation of manual and automated in situ hybridization platforms;Shahid;Am J Surg Pathol,2015

2. The ability to diagnose intrahepatic cholangiocarcinoma definitively using novel branched DNA-enhanced albumin RNA in situ hybridization technology;Ferrone;Ann Surg Oncol,2016

3. Albumin RNA in situ hybridization in hepatocellular carcinomas and other neoplastic and non-neoplastic tissue: can this be a clinically useful marker [abstract];Avadhani;Mod Pathol,2017

4. Is albumin RNA in situ hybridization (RISH) a reliable marker for intrahepatic cholangiocarcinomas [abstract];Avadhani;Mod Pathol,2017

5. Albumin in-situ hybridization may be positive in adenocarcinomas and other tumors from diverse sites [abstract];Lehrke;Mod Pathol,2017

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