Increased Risks for Suicide, Self-Harm, Substance Use, and Psychiatric Disorders in Adults With Inflammatory Bowel Disease: A Nationwide Study in the United States From 2007 to 2017

Author:

Tse Chung Sang1ORCID,Weng Chien-Hsiang2ORCID,Kwon Michelle3,Wolk Courtney Benjamin4,Brown Lily A245,Malani Kanika3,Shah Samir A67,Fine Sean D6

Affiliation:

1. Division of Gastroenterology, University of Pennsylvania , Philadelphia, PA , USA

2. Department of Family Medicine, Warren Alpert Medical School, Brown University , Providence, RI , USA

3. Warren Alpert Medical School, Brown University , Providence, RI , USA

4. Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA , USA

5. Center for the Treatment and Study of Anxiety, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA , USA

6. Division of Gastroenterology, Warren Alpert Medical School, Brown University , Providence, RI , USA

7. Gastroenterology Associates, Inc , Providence, RI , United States

Abstract

Lay Summary In an analysis of over 260 million emergency department visits across the United States from 2007 to 2017, inflammatory bowel disease conferred >10-fold risk for suicide deaths, self-harm, substance use, and psychiatric disorders, though the overall self-harm rates were low (<1% of all-cause inflammatory bowel disease emergency department visits; total 56 suicide deaths).

Funder

Brown Medicine

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,Immunology and Allergy

Reference11 articles.

1. The interpersonal theory of suicide;Van Orden;Psychol Rev.,2010

2. Update on the incidence and prevalence of inflammatory bowel disease in the United States;Loftus;Gastroenterol Hepatol (N Y),2016

3. Suicidal thoughts and behaviors among adults aged ≥18 years--United States, 2008-2009;Crosby,2011;60(13):1-22

4. Association of inflammatory bowel disease with suicidal ideation, suicide attempts, and suicide: a systematic review and meta-analysis;Xiong;J Psychosom Res.,2022

5. Suicidal behavior among hospitalized adults with inflammatory bowel disease: a United States Nationwide Analysis;Marchioni Beery;Inflamm Bowel Dis.,2017

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