Targeted Probiotics Against Bacterial-Fungal Biofilms: A New Concept Seems to Bring Us Closer to Microbiome-modulating Therapy for Inflammatory Bowel Disease-Reference-Cited by-同舟云学术

Targeted Probiotics Against Bacterial-Fungal Biofilms: A New Concept Seems to Bring Us Closer to Microbiome-modulating Therapy for Inflammatory Bowel Disease

Published:2023-09-06 Issue:11 Volume:29 Page:e40-e41
ISSN:1078-0998
Container-title:Inflammatory Bowel Diseases
language:en
Short-container-title:

Author:

Sitkin Stanislav¹²³^ORCID,Pokrotnieks Juris⁴⁵^ORCID

Affiliation:

1. Institute of Perinatology and Pediatrics, Almazov National Medical Research Centre , St. Petersburg , Russia

2. Department of Internal Diseases, Gastroenterology and Dietetics, North-Western State Medical University named after I.I. Mechnikov , St. Petersburg , Russia

3. Research and Development Department, Elpis Ltd., Riga , Latvia

4. Department of Internal Diseases, Rīga Stradiņš University , Riga , Latvia

5. Centre of Gastroenterology, Hepatology and Nutrition, Pauls Stradiņš Clinical University Hospital , Riga , Latvia

Abstract

Lay Summary This article describes the concept of microbiome-modulating therapy for inflammatory bowel diseases using targeted probiotics. A designed probiotic composition is discussed as an example, the targets for which are polymicrobial bacterial-fungal biofilms specific for Crohn’s disease.

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,Immunology and Allergy

Link

https://academic.oup.com/ibdjournal/advance-article-pdf/doi/10.1093/ibd/izad209/51392594/izad209.pdf

Reference10 articles.

1. A novel probiotic combination ameliorates Crohn’s disease-like ileitis by increasing short-chain fatty acid production and modulating essential adaptive immune pathways;Di Martino;Inflamm Bowel Dis.,2023

2. Effects of a novel probiotic combination on pathogenic bacterial-fungal polymicrobial biofilms;Hager;mBio,2019

3. Bacteriome and mycobiome interactions underscore microbial dysbiosis in familial Crohn’s disease;Hoarau;mBio,2016

4. Mycobiome and inflammatory bowel disease: role in disease pathogenesis, current approaches and novel nutritional-based therapies;Hsu;Inflamm Bowel Dis.,2023

5. Gut mycobiome and dysmycobiosis: clinical significance and therapeutic perspectives;Khavkin;Vopr. prakt. pediatr. (Clinical Practice in Pediatrics),2023