1-Year Comparison of Clinical and Endoscopic Outcomes of Tofacitinib vs Vedolizumab for Ulcerative Colitis After Anti-Tumor Necrosis Factor Failure: A Real-World Cohort Study in the United States-Reference-Cited by-同舟云学术

1-Year Comparison of Clinical and Endoscopic Outcomes of Tofacitinib vs Vedolizumab for Ulcerative Colitis After Anti-Tumor Necrosis Factor Failure: A Real-World Cohort Study in the United States

Published:2023-08-24 Issue: Volume: Page:
ISSN:1078-0998
Container-title:Inflammatory Bowel Diseases
language:en
Short-container-title:

Author:

Dalal Rahul S¹^ORCID,Sharma Puza P²,Bains Kanwal³,Pruce Jordan C¹,Allegretti Jessica R¹^ORCID

Affiliation:

1. Division of Gastroenterology, Hepatology and Endoscopy, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School , Boston, MA , USA

2. Pfizer Inc , New York, NY , USA

3. Department of Nutrition, Brigham and Women’s Hospital, Harvard Medical School , Boston, Massachusetts , USA

Abstract

In this retrospective cohort study, tofacitinib was associated with higher adjusted odds of steroid-free clinical remission at 52 weeks and endoscopic remission within 52 weeks compared with vedolizumab. Adverse events were consistent with the known safety profiles of these agents.

Funder

Pfizer

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology,Immunology and Allergy

Link

https://academic.oup.com/ibdjournal/advance-article-pdf/doi/10.1093/ibd/izad165/51248274/izad165.pdf

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5. Hospitalization outcomes for inflammatory bowel disease in teaching vs nonteaching hospitals;Dalal;Inflamm Bowel Dis.,2019

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