BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1–MCM2 signaling during pregnancy

Author:

Xu Xiaoling1,Chen Eric2,Mo Lihua1,Zhang Lei13,Shao Fangyuan1,Miao Kai1,Liu Jianlin1,Su Sek Man1,Valecha Monica1,Chan Un In1,Zheng Hongping2,Chen Mark2,Chen Weiping4,Chen Qiang1,Fu Haiqing5,Aladjem Mirit I5,He Yanzhen3,Deng Chu-Xia1ORCID

Affiliation:

1. Faculty of Health Sciences, University of Macau, Macau SAR, China

2. Genetics of Development and Disease Branch

3. Department of Vascular Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, 646000, China

4. Gene Expression Core, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD

5. Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

National Institutes of Health

University of Macau

Science and Technology Development Fund

Publisher

Oxford University Press (OUP)

Subject

Genetics(clinical),Genetics,Molecular Biology,General Medicine

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