International multicentre propensity score-matched analysis comparing robotic versus laparoscopic right posterior sectionectomy

Author:

Chiow Adrian K H1,Fuks David2,Choi Gi-Hong3,Syn Nicholas4ORCID,Sucandy Iswanto5,Marino Marco V6ORCID,Prieto Mikel7,Chong Charing C8ORCID,Lee Jae Hoon9,Efanov Mikhail10ORCID,Kingham T Peter11,Choi Sung Hoon12,Sutcliffe Robert P13,Troisi Roberto I14ORCID,Pratschke Johann15,Cheung Tan-To16ORCID,Wang Xiaoying17,Liu Rong18,D’Hondt Mathieu19,Chan Chung-Yip20,Tang Chung Ngai21,Han Ho-Seong22ORCID,Goh Brian K P20ORCID,D’Silva M,Schotte H,De Meyere C,Lai E,Krenzien F,Schmelzle M,Kadam P,Montalti R,Giglio M,Liu Q,Lee K F,Salimgereeva D,Alikhanov R,Lee L-S,Gastaca M,Jang J Y,

Affiliation:

1. Hepatopancreatobiliary Unit, Department of Surgery, Changi General Hospital, Singapore

2. Department of Digestive, Oncologic and Metabolic Surgery, Institute Mutualiste Montsouris, Universite Paris Descartes, Paris, France

3. Division of Hepatopancreatobiliary Surgery, Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea

4. Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and Yong Loo Lin School of Medicine, National University of Singapore, Singapore

5. AdventHealth Tampa, Digestive Health Institute, Tampa, Florida, USA

6. General Surgery Department, Azienda Ospedaliera Ospedali Riuniti Villa Sofia-Cervello, Palermo, Italy and Oncologic Surgery Department, P. Giaccone University Hospital, Palermo, Italy

7. Hepatobiliary Surgery and Liver Transplantation Unit, Biocruces Bizkaia Health Research Institute, Cruces University Hospital, University of the Basque Country, Bilbao, Spain

8. Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, New Territories, Hong Kong SAR, China

9. Department of Surgery, Division of Hepato-Biliary and Pancreatic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea

10. Department of Hepato-Pancreato-Biliary Surgery, Moscow Clinical Scientific Center, Moscow, Russia

11. Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA

12. Department of General Surgery, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea

13. Department of Hepatopancreatobiliary and Liver Transplant Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

14. Department of Clinical Medicine and Surgery, Division of HPB, Minimally Invasive and Robotic Surgery, Federico II University Hospital Naples, Naples, Italy

15. Department of Surgery, Campus Charité Mitte and Campus Virchow-Klinikum, Charité-Universitätsmedizin, Corporate Member of Freie Universität Berlin, and Berlin Institute of Health, Berlin, Germany

16. Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China

17. Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai, China

18. Faculty of Hepatopancreatobiliary Surgery, The First Medical Center of Chinese People’s Liberation Army (PLA) General Hospital, Beijing, China

19. Department of Digestive and Hepatobiliary/Pancreatic Surgery, Groeninge Hospital, Kortrijk, Belgium

20. Department of Hepatopancreatobiliary and Transplant Surgery, Singapore General Hospital and Duke-National University Singapore Medical School, Singapore

21. Department of Surgery, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China

22. Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seoul, Korea

Abstract

Abstract Background Minimally invasive right posterior sectionectomy (RPS) is a technically challenging procedure. This study was designed to determine outcomes following robotic RPS (R-RPS) and laparoscopic RPS (L-RPS). Methods An international multicentre retrospective analysis of patients undergoing R-RPS versus those who had purely L-RPS at 21 centres from 2010 to 2019 was performed. Patient demographics, perioperative parameters, and postoperative outcomes were analysed retrospectively from a central database. Propensity score matching (PSM) was performed, with analysis of 1 : 2 and 1 : 1 matched cohorts. Results Three-hundred and forty patients, including 96 who underwent R-RPS and 244 who had L-RPS, met the study criteria and were included. The median operating time was 295 minutes and there were 25 (7.4 per cent) open conversions. Ninety-seven (28.5 per cent) patients had cirrhosis and 56 (16.5 per cent) patients required blood transfusion. Overall postoperative morbidity rate was 22.1 per cent and major morbidity rate was 6.8 per cent. The median postoperative stay was 6 days. After 1 : 1 matching of 88 R-RPS and L-RPS patients, median (i.q.r.) blood loss (200 (100–400) versus 450 (200–900) ml, respectively; P < 0.001), major blood loss (> 500 ml; P = 0.001), need for intraoperative blood transfusion (10.2 versus 23.9 per cent, respectively; P = 0.014), and open conversion rate (2.3 versus 11.4 per cent, respectively; P = 0.016) were lower in the R-RPS group. Similar results were found in the 1 : 2 matched groups (66 R-RPS versus 132 L-RPS patients). Conclusion R-RPS and L-RPS can be performed in expert centres with good outcomes in well selected patients. R-RPS was associated with reduced blood loss and lower open conversion rates than L-RPS.

Publisher

Oxford University Press (OUP)

Subject

Surgery

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