Microsatellite instability in young patients with rectal cancer: molecular findings and treatment response
Author:
, Zaborowski Alexandra MORCID, Abdile Ahmed, Adamina Michel, Aigner Felix, d'Allens Laura, Allmer Caterina, Álvarez Andrea, Anula Rocio, Andric Mihailo, Atallah Sam, Bach Simon, Bala Miklosh, Barussaud Marie, Bausys Augustinas, Beggs Andrew, Bellolio Felipe, Bennett Melissa-Rose, Berdinskikh Anton, Bevan Vicki, Biondo Sebastiano, Bislenghi Gabriele, Bludau Marc, Brouwer Nelleke, Brown Carl, Bruns Christiane, Buchanan Daniel D, Buchwald Pamela, Burger Jacobus W A, Burlov Nikita, Campanelli Michela, Capdepont Maylis, Carvello Michele, Chew Hwee-Hoon, Christoforidis Dimitri, Clark David, Climent Marta, Collinson Rowan, Cologne Kyle G, Contreras Tomas, Croner Roland, Daniels Ian R, Dapri Giovanni, Davies Justin, Delrio Paolo, Denost Quentin, Deutsch Michael, Dias Andre, D'Hoore André, Drozdov Evgeniy, Duek Daniel, Dunlop Malcolm, Dziki Adam, Edmundson Aleksandra, Efetov Sergey, El-Hussuna Alaa, Elliot Brodie, Emile Sameh, Espin Eloy, Evans Martyn, Faes Seraina, Faiz Omar, Figueiredo Nuno, Fleming Fergal, Foppa Caterina, Fowler George, Frasson Matteo, Forgan Tim, Frizelle Frank, Gadaev Shamil, Gellona Jose, Glyn Tamara, Goran Barisic, Greenwood Emma, Guren Marianne G, Guillon Stephanie, Gutlic Ida, Hahnloser Dieter, Hampel Heather, Hanly Ann, Hasegawa Hirotoshi, Iversen Lene Hjerrild, Hill Andrew, Hill James, Hoch Jiri, Hompes Roel, Hurtado Luis, Iaquinandi Fabiano, Imbrasaite Ugne, Islam Rumana, Jafari Mehrenah D, Salido Andrea Jiménez, Jiménez Toscano Marta, Kanemitsu Yukihide, Karachun Aleksei, Karimuddin Ahmer A, Keller Deborah S, Kelly Justin, Kennelly Rory, Khrykov Gleb, Kocian Peter, Koh Cherry, Kok Neils, Knight Katrina A, Knol Joep, Kontovounisios Christos, Korner Hartwig, Krivokapic Zoran, Kronberger Irmgard, Kroon Hidde Maarten, Kryzauskas Marius, Kural Said, Kusters Miranda, Lakkis Zaher, Lankov Timur, Larson David, Lázár György, Lee Kai-Yin, Lee Suk Hwan, Lefèvre Jérémie H, Lepisto Anna, Lieu Christopher, Loi Lynette, Lynch Craig, Maillou-Martinaud Helene, Maroli Annalisa, Martin Sean, Martling Anna, Matzel Klaus E, Mayol Julio, McDermott Frank, Meurette Guillaume, Millan Monica, Mitteregger Martin, Moiseenko Andrei, Monson John R T, Morarasu Stefan, Moritani Konosuke, Möslein Gabriela, Munini Martino, Nahas Caio, Nahas Sergio, Negoi Ionut, Novikova Anastasia, Ocares Misael, Okabayashi Koji, Olkina Alexandra, Oñate-Ocaña Luis, Otero Jaime, Ozen Cihan, Pace Ugo, Julião Guilherme Pagin São, Panaiotti Lidiia, Panis Yves, Papamichael Demetris, Patel Swati, Uriburu Juan Carlos Patrón, Peng Sze-Lin, Pera Miguel, Perez Rodrigo O, Petrov Alexei, Pfeffer Frank, Phang Terry P, Poskus Tomas, Pringle Heather, Proud David, Raguz Ivana, Rama Nuno, Rasheed Shahnawaz, Raval Manoj J, Rega Daniela, Reissfelder Christoph, Meneses Juan Carlos Reyes, Ris Frederic, Riss Stefan, Rodriguez-Zentner Homero, Roxburgh Campbell S, Saklani Avanish, Sammour Tarik, Saraste Deborah, Schneider Martin, Seishima Ryo, Sekulic Aleksander, Seppala Toni, Sheahan Kieran, Shlomina Alexandra, Sigismondo Guiseppe, Singnomklao Tongplaew, Siragusa Leandro, Smart Neil, Solis-Peña Alejandro, Spinelli Antonino, Staiger Roxane D, Stamos Michael J, Steele Scott, Tan Ker-Kan, Tanis Pieter J, Tekkis Paris, Teklay Biniam, Tengku Sabrina, Tsarkov Petr, Turina Matthias, Ulrich Alexis, Vailati Bruna B, van Harten Meike, Verhoef Cornelis, Warrier Satish, Wexner Steven, de Wilt Hans, Weinberg Benjamin A, Wells Cameron, Wolthuis Albert, Xynos Evangelos, You Nancy, Zakharenko Alexander, Zeballos Justino, Zhou Jonathan, Winter Des C
Abstract
In this study of 400 patients with early-onset rectal cancer, 12.5 per cent demonstrated microsatellite instability (MSI). MSI was associated with a reduced likelihood of nodal positivity, an increased rate of pathological complete response, and improved disease-specific survival.
Publisher
Oxford University Press (OUP)
Cited by
12 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
|
|