A pharmacy-led sore throat test and treat (STTT) service: antigen testing and antibiotic supply rates during the period of heightened public awareness of Group A Streptococcus infections

Author:

Mantzourani Efi12ORCID,Ahmed Haroon3ORCID,Evans Andrew4,Gunnarsson Ronny567,Cannings-John Rebecca8

Affiliation:

1. Cardiff School of Pharmacy and Pharmaceutical Sciences, Cardiff University , Redwood Building, King Edward VII Avenue, Cardiff CF10 3NB, Wales , UK

2. Clinical Informatics, Digital Health and Care Wales, NHS Wales , Cardiff, Wales , UK

3. Division of Population Medicine, Cardiff University , Cardiff, Wales , UK

4. Primary Care Services, Welsh Government , Cardiff, Wales , UK

5. School of Public Health and Community Medicine, University of Gothenburg , Gothenburg , Sweden

6. Region Västra Götaland, Research, Development, Education and Innovation, Primary Health Care , Gothenburg , Sweden

7. Centre for Antibiotic Resistance Research (CARe) at University of Gothenburg , Gothenburg , Sweden

8. Centre for Trials Research, Cardiff University , Cardiff, Wales , UK

Abstract

Abstract Background Community pharmacies in Wales delivered an NHS-funded sore throat test and treat (STTT) service during the period of increased invasive Group A Streptococcus (iGAS) incidents in winter 2022–23. Service users were screened using FeverPAIN/CENTOR scores, offered GAS rapid antigen detection tests (RADT) if appropriate, and antibiotics if indicated. Objectives To evaluate the service’s response to a substantial rise in sore throat presentations during a period of heightened public anxiety. Methods Cross-sectional study with anonymized individual-level data from electronic pharmacy records of all eligible STTT service users, between January 2022 and March 2023. Results Antibiotics were supplied to 24% (95% CI: 23–24) of people who used the STTT service and 31% (95% CI: 31–32) of those who met the threshold for an RADT. Of 27 441 STTT consultations, 9308 (33.9%) occurred during December 2022. In the week commencing 2 December 2022, following the announcements of increased iGAS incidents, we observed a statistically significant increase of 1700 consultations (95% CI: 924–2476) and a statistically significant decrease in supply rate of 13.9 antibiotics per 100 RADT (95% CI: −18.40 to −9.40). Antibiotic supply rates increased thereafter to those observed before the announcements of iGAS incidents. Referral rates to other primary care or emergency settings remained below 10% throughout the study period. Conclusions Our findings suggest that, despite a dramatic increase in sore throat consultation rates in response to media reports, the pre-specified pathway followed by pharmacists ensured appropriate use of antibiotics, and absorbed a substantial workload that would otherwise end up in other healthcare settings.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

Reference23 articles.

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2. Antibiotics for treatment of sore throat in children and adults;Spinks;Cochrane Database Syst Rev,2021

3. Efficacy and safety of rapid tests to guide antibiotic prescriptions for sore throat;Cohen;Cochrane Database Syst Rev,2020

4. Epidemiology of invasive group A streptococcal infections in the United States, 2005–2012;Nelson;Clin Infect Dis,2016

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