1. Department of Epidemiology and Biostatistics, Michigan State University , East Lansing, MI 48824, USA
2. Institute for Quantitative Health Science and Engineering, Systems Biology, Michigan State University , East Lansing, MI 48824, USA
3. Department of Medicine, The University of Alabama at Birmingham , Birmingham, AL 35294, USA
4. Department of Biochemistry, University of Otago , Dunedin 9016, New Zealand
5. Liggins Institute, The University of Auckland , Auckland 1142, New Zealand
6. Department of Statistics and Probability, Michigan State University , East Lansing, MI 48824, USA