1. Department of Neurosciences, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy, 2European Molecular Biology Laboratory (EMBL), Mouse Biology Unit, Via Ramarini 32, 00015 Monterotondo, Italy, and 3Santa Lucia Foundation, European Centre for Brain Research (CERC), Via del Fosso di Fiorano 64/65, 00143 Rome, Italy