‘Europe’, ‘Europeans’, and ‘Europeanness’ have been crucial themes in the history of modern Greece, from the creation of the new state in 1832 to the sovereign debt crisis of 2010. As elsewhere, these notions have served as référentiels in questions of national identity, progress, capability, legitimation and strategic interest. In the Greek case, the European dimension to these questions has been felt acutely. This chapter considers Greece’s political development in the context of its membership of the European Union, assessing the extent to which the latter has prompted domestic reform. A general theme that emerges from the scholarly literature in this area is of Greece’s uneven adaptation across different sectors, a feature that provokes interesting research contrasts, but also challenges of interpretation. To understand how EU pressures for adaptation have been received domestically, the chapter opens with a discussion of the changing images and meanings of ‘Europe’ in Greece. This is followed by an assessment of the range and significance of the domestic adaptation of policies and regulations to EU legislation, as established by existing academic studies and policy papers. We note the current state of knowledge of Europeanization impacts on Greece, the implications of the findings, and pointers for future research. The unevenness of adaptation is an essential lens for analysis.